Santonin Analogs. III. : On Monocarboxylic Acid obtained from Dihydroalantolactone.

Monocarboxylic acid transport.

Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in metabolism and must be transported across both the plasma membrane and mitochondrial inner membrane. A family of five proton-linked MonoCarboxylate Transporters (MCTs) is involved in the former and the mitochondrial pyruvate carrier (MPC) mediates the latter. In the intestine and kidney, two Sodium-coupled Mon...

Anthelmintic Properties of Santonin'

In the world of therapeutics certain drugs or preparations have been used for so many years that the statements in the literature, especially in the textbooks and also in articles in professional journals, as to the action of these drugs have a tendency to reiterate impressionistic ideas or traditions. Printed statements are ordinarily copied and passed on with little or no attempt to substanti...

The Price of Santonin

To the Editor, "The Indian Medical G ^ \ouv . Sir,?Comment was made in a readers will be Journal on the price of santonin. 0 .< announced a 'nterested to know that we have rece well-known substantial reduction in the price o auantities is drug. Our reduced price for wholesaic 1 ^ per. e(iuivalent to about 29s. 9d. per oz., explanation?1 pain. Our new scale of prices and November nave appeared i...

Monoamino monocarboxylic acid content of preparations of herbage protein.

Microbial Transformations of α-Santonin

Fungal biotransformations of α-santonin (1) were conducted with Mucor plumbeus (ATCC 4740), Cunninghamella bainieri (ATCC 9244), Cunninghamella echinulata (ATCC 9245), Curvularia lunata (ATCC 12017) and Rhizopus stolonifer (ATCC 10404). Rhizopus stolonifer (ATCC 10404) metabolized compound 1 to afford 3,4-epoxy-α-santonin (2) and 4,5-dihydroα-santonin (3) while Cunninghamella bainieri (ATCC 924...